Medicine

Advancing ASO therapies coming from progression to application

.Contending passions.R.S., M.S., H.G. and also A.A.R. are organizers of the 1M1M project. H.G. as well as A.A.R. are panel of supervisors participants as well as R.S., M.S. as well as A.A.R. are actually participants of the medical advising committee of N1C. A.A.R. divulges employment through LUMC, which possesses licenses on exon-skipping technology, some of which has actually been actually accredited to BioMarin and also subsequently sublicensed to Sarepta. As co-inventor of a number of these patents, A.A.R. was actually qualified to a share of nobilities. A.A.R. better makes known serving as impromptu expert for PTC Therapies, Sarepta Rehabs, Regenxbio, Dyne Therapeutics, Lilly, BioMarin Pharmaceuticals Inc., Eisai, Entrada, Takeda, Splicesense, Galapagos, Sapreme, Italfarmaco and also Astra Zeneca. Previously 5 years, A.A.R. additionally carried out consulting for Alpha Anomeric. A.A.R. additionally mentions subscription of the clinical boards of advisers of Eisai, Hybridize Rehabs, Muteness Rehabs, Sarepta Therapies, Sapreme as well as Mitorx. Over the last 5 years, A.A.R. was also a scientific board of advisers member for ProQR. Reimbursement for A.A.R. u00e2 s consulting and also advising tasks is actually spent to LUMC. In the past 5 years, LUMC additionally received audio speaker honoraria from PTC Therapies, Alnylam Netherlands, Italfarmaco as well as Pfizer as well as funding for arrangement research study from Sapreme, Eisai, Galapagos, Synaffix and also Alpha Anomeric. Job funding is actually gotten coming from Sarepta Therapies and also Entrada via unlimited grants. H.G. has nothing at all to reveal in regard to the subject matters dealt with in this particular document. In the past 5 years, he has actually likewise obtained consultancy gratuity from UCB. M.S. got consultancy honoraria from Ionis, UCB, Prevail, Orphazyme, Biogen, Servier, Reata, GenOrph, AviadoBio, Biohaven, Zevra, Lilly as well as Solaxa previously 5 years, all unassociated to the here and now document. R.S. has nothing to make known in connection with the subject matters dealt with in this particular composition. She has acquired sound speaker and/or working as a consultant gratuity or funding contributions coming from Abbvie, Bial, STADA and also Everpharma over the last 5 years.